Cert Clin Haematology(SA) Path Practice Questions - CMSA Sub-specialty Certificate In Clinical Haematology (Pathology) Exam

Which cytochemical stain pattern is classic for acute promyelocytic leukemia (APL) with PML-RARA fusion?

Tartrate-resistant acid phosphatase (TRAP) strongly positive Strongly, diffusely Myeloperoxidase (MPO) positive and Sudan Black B (SBB) positive Nonspecific esterase (NSE) strongly positive and completely inhibited by sodium fluoride Periodic acid-Schiff (PAS) positive in a block-like cytoplasmic pattern

Correct Answer:

Strongly, diffusely Myeloperoxidase (MPO) positive and Sudan Black B (SBB) positive

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