Befähigungsprüfung Drogisten Practice Questions - Befähigungsprüfung Drogisten (Austria) Exam

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When dispensing St. John's Wort (Hyperici herba) preparations in a drugstore, which critical pharmacological interactions and risks must the Drogist explain to the customer?

Severe anticholinergic urinary retention and increased intraocular pressure in open-angle glaucoma Immediate irreversible inhibition of monoamine oxidase-A requiring a strict tyramine-free diet Induction of cytochrome P450 (CYP3A4) and P-glycoprotein leading to reduced blood levels of oral contraceptives and immunosuppressants, alongside photosensitivity Hyperuricemia causing acute gouty arthritis through competitive inhibition of renal uric acid excretion

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Induction of cytochrome P450 (CYP3A4) and P-glycoprotein leading to reduced blood levels of oral contraceptives and immunosuppressants, alongside photosensitivity

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