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ABPath Neuropathology Practice Questions - ABPath Neuropathology Subspecialty Certification Examination Exam

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A 22-year-old presents with a hemispheric high-grade glioma. Sequencing shows H3.3 G34R mutation with ATRX loss and TP53 mutation. Which WHO CNS 2021 tumor is this?
Correct Answer:
Diffuse hemispheric glioma, H3 G34-mutant, CNS WHO grade 4

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