Cert Medical Oncology(SA) Paed Practice Questions - CMSA Sub-specialty Certificate In Medical Oncology Cert Medical Oncology(SA) Paed - South Africa Exam

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Minimal residual disease (MRD) measurement at the end of induction chemotherapy is the most powerful post-treatment prognostic marker in paediatric ALL. What threshold measured by flow cytometry or quantitative PCR is standardly used to define MRD negativity?

Less than 0.0001% (< 1 in 1,000,000 cells / 10^-6) Less than 0.01% (< 1 in 10,000 cells / 10^-4) Less than 0.1% (< 1 in 1,000 cells / 10^-3) Less than 1.0% (< 1 in 100 cells / 10^-2)

Correct Answer:

Less than 0.01% (< 1 in 10,000 cells / 10^-4)

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