ABP Pediatric Hematology-Oncology Practice Questions - ABP Pediatric Hematology-Oncology Subspecialty Certification Examination Exam

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At end-of-induction for pediatric B-ALL, flow cytometric MRD shows 0.05% residual blasts. What does this finding indicate?

Immediate HSCT regardless of other risk factors Excellent response; de-escalate therapy Remission by morphology makes MRD irrelevant Poor prognosis and need for treatment intensification

Correct Answer:

Poor prognosis and need for treatment intensification

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