Cert Nephrology(SA) Phys Practice Questions - Sub-specialty Certificate In Nephrology Of The College Of Physicians Of South Africa Exam

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A 54-year-old male develops a rise in serum creatinine from 90 to 280 µmol/L three weeks after starting omeprazole for gastro-esophageal reflux disease. Urinalysis reveals sterile pyuria and white blood cell casts. What is the most definitive diagnostic test to establish the diagnosis?

Gallium-67 renal scintigraphy scan showing diffuse uptake Urinary eosinophil testing using Hansel stain Serum IgE elevation and peripheral blood eosinophilia count Percutaneous renal biopsy showing tubulointestinal inflammatory infiltrate with eosinophils

Correct Answer:

Percutaneous renal biopsy showing tubulointestinal inflammatory infiltrate with eosinophils

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