TEOC Oncologia Clínica Practice Questions - TEOC - Título De Especialista Em Oncologia Clínica (Sociedade Brasileira De Oncologia Clínica AMB) Exam

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A 56-year-old postmenopausal woman undergoes breast-conserving surgery and axillary lymph node dissection for a 4.5 cm invasive ductal carcinoma. Pathology confirms ER 95%, PR 80%, HER2 1+ (negative), Ki-67 35%, and 5 out of 14 lymph nodes positive for macrometastases (pT2 pN2a cM0, Stage IIIA). She completes adjuvant dose-dense AC followed by paclitaxel and adjuvant radiotherapy. According to the monarchE phase III trial, which targeted agent should be added to her adjuvant endocrine therapy?
Correct Answer:
Abemaciclib 150 mg twice daily continuously for 2 years

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