Register
Question 1
A 42-year-old premenopausal woman presents with a palpable 3.2 cm mass in the upper outer quadrant of the right breast. Core needle biopsy confirms invasive ductal carcinoma, histological grade 3, estrogen receptor (ER) 0%, progesterone receptor (PR) 0%, and HER2 immunohistochemistry 0 (triple-negative breast cancer). Right axillary ultrasound-guided fine needle aspiration reveals metastatic carcinoma in one lymph node (cT2 cN1 cM0, Stage IIB). Based on the landmark KEYNOTE-522 trial and SBOC guidelines, what is the standard neoadjuvant systemic therapy regimen for this patient?
Correct Answer:
Neoadjuvant pembrolizumab combined with carboplatin and paclitaxel, followed by pembrolizumab with doxorubicin (or epirubicin) and cyclophosphamide, followed after definitive surgery by adjuvant pembrolizumab to complete 1 year.
Question 2
A 56-year-old postmenopausal woman undergoes breast-conserving surgery and axillary lymph node dissection for a 4.5 cm invasive ductal carcinoma. Pathology confirms ER 95%, PR 80%, HER2 1+ (negative), Ki-67 35%, and 5 out of 14 lymph nodes positive for macrometastases (pT2 pN2a cM0, Stage IIIA). She completes adjuvant dose-dense AC followed by paclitaxel and adjuvant radiotherapy. According to the monarchE phase III trial, which targeted agent should be added to her adjuvant endocrine therapy?
Correct Answer:
Abemaciclib 150 mg twice daily continuously for 2 years
Question 3
A 38-year-old woman with a documented germline BRCA1 pathogenic mutation is diagnosed with triple-negative invasive breast cancer. She completes neoadjuvant dose-dense AC followed by carboplatin/paclitaxel and undergoes mastectomy with sentinel node biopsy. Surgical pathology reveals a 1.2 cm residual invasive carcinoma in the breast and 1 micrometastatic lymph node (non-pCR, residual cancer burden class II). According to the OlympiA trial, which adjuvant targeted therapy provides a proven overall survival benefit?
Correct Answer:
Olaparib 300 mg twice daily orally for 1 year
Question 4
A 48-year-old woman with cT2 cN1 HER2-positive (IHC 3+, ER/PR negative) invasive ductal carcinoma completes neoadjuvant chemotherapy consisting of 6 cycles of docetaxel, carboplatin, trastuzumab, and pertuzumab (TCHP). She undergoes lumpectomy and sentinel node biopsy. Histopathology shows a 1.4 cm residual invasive tumor with 2 positive lymph nodes (ypT1c ypN1a). According to the KATHERINE trial, what is the most appropriate adjuvant systemic therapy?
Correct Answer:
Trastuzumab emtansine (T-DM1) 3.6 mg/kg intravenously every 3 weeks for 14 cycles
Question 5
A 34-year-old premenopausal woman with high-risk luminal B breast cancer (ER 90%, PR 10%, HER2 0, grade 3, pT2 pN1a with 3 positive lymph nodes) completes adjuvant chemotherapy and radiotherapy. Her menstrual cycles resume 3 months later. Based on the joint analysis of the SOFT and TEXT trials, which endocrine therapy strategy provides the greatest reduction in breast cancer recurrence?
Correct Answer:
Ovarian function suppression (GnRH agonist) plus an aromatase inhibitor (exemestane) for 5 years
Question 1
Exam overview

About this Exam

Prepare with the TEOC Oncologia Clínica Practice Questions - TEOC - Título de Especialista em Oncologia Clínica (Sociedade Brasileira de Oncologia Clínica AMB) Exam practice quiz. This question bank includes 100 questions covering year-old, trial, metastatic, woman, and cancer. Use it to review important concepts, identify knowledge gaps, and build confidence for the related exam, course, or assessment.

More details

Additional Information

TEOC Oncologia Clínica Practice Questions - TEOC - Título de Especialista em Oncologia Clínica (Sociedade Brasileira de Oncologia Clínica AMB) Exam

This practice set contains 100 questions from the matching question bank and focuses on year-old, trial, metastatic, woman, and cancer. Work through each question carefully, review the provided solutions, and revisit topics that need more study before your next attempt.

This is an independent study resource intended for practice and review; it is not an official examination or an endorsement by any organization named in the title.

Quiz information

Frequently Asked Questions

The complete question count is available after full access is unlocked.
No fixed duration is currently configured for this quiz.
Question explanations are included where they are available in the quiz content, helping you review the reasoning after answering.
Yes. You can retake the practice test again as you continue studying during your available access period.
After your access is confirmed, you can continue into the complete practice exam from this quiz flow.
Unless explicitly stated otherwise, this page provides independent practice material for study and exam preparation and is not the official examination itself.
Keep studying

Related Questions

ABIN Agente de Inteligência Practice Questions - Agência Brasileira de Inteligência (ABIN) - Agente de Inteligência Exam

0 min

ABIN Oficial de Inteligência Practice Questions - Agência Brasileira de Inteligência (ABIN) - Oficial de Inteligência Exam

0 min

ABTER Proteção Radiológica Practice Questions - ABTER Prova de Título de Especialista em Supervisão de Proteção Radiológica no Radiodiagnóstico Exam

0 min

CBC Título de Especialista em Cirurgia Geral Practice Questions - Exame para Obtenção do Título de Especialista em Cirurgia Geral - CBC AMB Exam

0 min

CBR Prova de Título de Especialista em Radiologia e Diagnóstico por Imagem (Brazil) Practice Questions - CBR Prova de Título de Especialista em Radiologia e Diagnóstico por Imagem (RDDI) Exam

0 min

COFFITO Título de Especialista Profissional Practice Questions - Exame Nacional para Concessão do Título de Especialista Profissional - COFFITO Exam

0 min