Cert Cardiology(SA) Phys Practice Questions - Sub-specialty Certificate In Cardiology Of The College Of Physicians Of South Africa Exam

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A 54-year-old male presents to a rural district hospital in the Eastern Cape 90 minutes after the onset of severe substernal chest pain. His ECG shows 4 mm ST-segment elevation in leads V1-V4 with reciprocal ST depression in II, III, and aVF. Transfer time to the nearest PCI-capable hospital is estimated at 3.5 hours. He has no contraindications to fibrinolysis. According to ESC and SA Heart guidelines, what is the most appropriate initial reperfusion strategy?
Correct Answer:
Immediate administration of a weight-adjusted bolus of tenecteplase (fibrinolysis) followed by urgent transfer for pharmacoinvasive PCI

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