Título De Especialista Em Infectologia SBI Practice Questions - Título De Especialista Em Infectologia (SBI AMB) Exam

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A 31-year-old female nurse sustains a deep percutaneous needle stick injury with a hollow-bore needle visibly contaminated with blood from an HIV-positive patient whose viral load is 85,000 copies/mL. The injury occurred 4 hours ago. According to Brazilian PCDT protocols for Post-Exposure Prophylaxis (PEP), what is the most appropriate management?

Initiate Tenofovir disoproxil fumarate (300 mg) + Lamivudine (300 mg) + Dolutegravir (50 mg) once daily for exactly 28 days, initiated within 72 hours of exposure Initiate Zidovudine + Lamivudine + Efavirenz for 14 days, provided the source patient's CD4 count is < 200 cells/mm³ Perform immediate baseline HIV PCR and delay antiretroviral prophylaxis until test results confirm transmission Administer a single loading dose of intramuscular Cabotegravir and prescribe oral Raltegravir for 7 days

Correct Answer:

Initiate Tenofovir disoproxil fumarate (300 mg) + Lamivudine (300 mg) + Dolutegravir (50 mg) once daily for exactly 28 days, initiated within 72 hours of exposure

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