Cert Gastroenterology(SA) Phys Practice Questions - CMSA Sub-specialty Certificate In Gastroenterology Cert Gastroenterology(SA) Phys - South Africa Exam

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A 28-year-old female presents with a 6-week history of 5 to 6 bloody bowel movements daily, left lower quadrant abdominal cramping, and tenesmus. Sigmoidoscopy reveals continuous mucosal erythema, loss of vascular pattern, and granularity extending from the rectum up to 35 cm. Biopsies confirm chronic ulcerative colitis. Which of the following is the most appropriate first-line induction and maintenance regimen?

Topical mesalazine 1 g suppository daily combined with oral mesalazine 2.4 g to 4.8 g daily Oral mesalazine 1.2 g daily alone Oral prednisone 40 mg daily as monotherapy Intravenous infliximab 5 mg/kg at weeks 0, 2, and 6

Correct Answer:

Topical mesalazine 1 g suppository daily combined with oral mesalazine 2.4 g to 4.8 g daily

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