ABIM Med Oncology Practice Questions - ABIM Medical Oncology Subspecialty Certification Exam

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A 48-year-old woman with clinical stage II, ER 2%, PR 0%, HER2 0 (triple-negative) breast cancer is planned for neoadjuvant therapy. Based on KEYNOTE-522, which regimen is preferred?

AC followed by weekly paclitaxel, no immunotherapy Carboplatin + paclitaxel followed by AC plus pembrolizumab, then adjuvant pembrolizumab TCHP (docetaxel, carboplatin, trastuzumab, pertuzumab) Olaparib monotherapy

Correct Answer:

Carboplatin + paclitaxel followed by AC plus pembrolizumab, then adjuvant pembrolizumab

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