MRCPCH TAS Practice Questions - MRCPCH Theory And Science (TAS) Exam

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Neonates handle many drugs differently from adults. Compared with adults, which pharmacokinetic feature is characteristic of the term neonate?

Reduced volume of distribution for water-soluble drugs Increased total body water as a proportion of body weight Faster hepatic glucuronidation of drugs such as morphine Higher plasma albumin concentration than in adults

Correct Answer:

Increased total body water as a proportion of body weight

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