Cert Medical Oncology(SA) Paed Practice Questions - CMSA Sub-specialty Certificate In Medical Oncology Cert Medical Oncology(SA) Paed - South Africa Exam

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A 13-year-old adolescent boy presents with a 2-week history of worsening shortness of breath, facial puffiness, orthopnoea, and venous distension over the upper chest. Chest radiograph demonstrates a massive anterior mediastinal mass with left pleural effusion. Full blood count reveals WBC 145 x 10^9/L with 85% circulating blasts. What is the most likely diagnosis?
Correct Answer:
T-cell acute lymphoblastic leukaemia (T-ALL)

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