American Board Of Pathology (ABPath) Clinical Pathology Certification Exam

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A blood bank technologist is resolving an ABO discrepancy. The forward typing shows A positive, while the reverse typing is consistent with group O (anti-A and anti-B are reactive). The patient is a 75-year-old male with multiple myeloma. What is the most likely cause of this discrepancy?

A weak subgroup of A Recent transfusion with group O red cells Cold agglutinins Rouleaux formation

Correct Answer:

Rouleaux formation

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