Question 1
A 68-year-old male with a history of myelodysplastic syndrome receives a transfusion of 2 units of packed red blood cells. Five days later, he presents with a low-grade fever, mild jaundice, and a greater than expected drop in his hemoglobin level. A direct antiglobulin test (DAT) is now positive. Which of the following is the most likely cause of this presentation?
Correct Answer:
Delayed hemolytic transfusion reaction
Question 2
A blood bank technologist is resolving an ABO discrepancy. The forward typing shows A positive, while the reverse typing is consistent with group O (anti-A and anti-B are reactive). The patient is a 75-year-old male with multiple myeloma. What is the most likely cause of this discrepancy?
Correct Answer:
Rouleaux formation
Question 3
Which of the following is the primary reason for irradiating cellular blood components?
Correct Answer:
To prevent transfusion-associated graft-versus-host disease (TA-GVHD)
Question 4
A patient with disseminated intravascular coagulation (DIC) and significant hypofibrinogenemia requires factor replacement. Which blood component is the most concentrated source of fibrinogen?
Correct Answer:
Cryoprecipitate
Question 5
A patient develops acute respiratory distress, hypoxemia, and bilateral pulmonary infiltrates on chest X-ray within 2 hours of receiving a platelet transfusion. There are no signs of circulatory overload. Which of the following is the most likely diagnosis?
Correct Answer:
Transfusion-Related Acute Lung Injury (TRALI)
Question 1
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Prepare with the American Board of Pathology (ABPath) Clinical Pathology Certification Exam practice quiz. This question bank includes 287 questions covering year-old, patient, cells, shows, and male. Use it to review important concepts, identify knowledge gaps, and build confidence for the related exam, course, or assessment.

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American Board of Pathology (ABPath) Clinical Pathology Certification Exam

This practice set contains 287 questions from the matching question bank and focuses on year-old, patient, cells, shows, and male. Work through each question carefully, review the provided solutions, and revisit topics that need more study before your next attempt.

This is an independent study resource intended for practice and review; it is not an official examination or an endorsement by any organization named in the title.

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