CRNI CERTIFIED
REGISTERED NURSE
INFUSION PRACTICE
EXAM 2026 COMPLETE
Question 1: Which upper-arm vein is often preferred for PICC insertion because it is usually large and follows a relatively straight course toward the central circulation?
Choices:
1) Cephalic vein 2) Basilic vein 3) Radial vein 4) Dorsal metacarpal vein
Correct Answer: Basilic vein
Explanation: The basilic vein is commonly favored for PICC placement because it generally has a larger diameter and a straighter path than the cephalic vein. Those characteristics can facilitate catheter advancement and reduce mechanical di�culty.Page 1
Question 2: A nurse is selecting a short peripheral catheter for an adult with fragile veins who needs routine isotonic IV �uids. Which principle best preserves venous blood �ow?
Choices:
1) Choose the largest gauge available 2) Use the smallest gauge that can safely deliver the prescribed therapy 3) Select a catheter that occupies most of the vein lumen 4) Choose catheter size based only on the patient's age Correct Answer: Use the smallest gauge that can safely deliver the prescribed therapy Explanation: Using the smallest catheter gauge that can safely deliver the prescribed therapy helps preserve blood �ow around the catheter and reduces mechanical irritation of the vein.Device choice should re�ect therapy requirements and patient-speci�c vessel characteristics.
Question 3: Before removing a non-tunneled internal jugular central venous
catheter from a patient who can tolerate positioning, which position best reduces the risk of venous air entry?
Choices:
1) High-Fowler position 2) Reverse Trendelenburg position 3) Trendelenburg or �at supine with the site below heart level 4) Sitting upright with the neck extended Correct Answer: Trendelenburg or �at supine with the site below heart level Explanation: Positioning the patient �at or in Trendelenburg raises central venous pressure and keeps the catheter exit site at or below the level of the heart. This reduces the pressure gradient that can draw air into the venous circulation during catheter removal.Page 2
Question 4: During removal of a central venous catheter from an alert adult, which respiratory instruction helps reduce the risk of air embolism?
Choices:
1) Take repeated rapid breaths 2) Perform a Valsalva maneuver or hold the breath at end-expiration as directed 3) Cough forcefully during removal 4) Inhale deeply while the catheter is withdrawn Correct Answer: Perform a Valsalva maneuver or hold the breath at end-expiration as directed Explanation: A Valsalva maneuver or removal during breath-holding at end-expiration increases intrathoracic and central venous pressure, making air entry less likely. The exact technique should follow organizational policy and the patient's ability to cooperate.
Question 5: Where should the tip of an upper-body central venous access device
generally terminate for central infusion therapy?
Choices:
1) In the brachiocephalic vein 2) At the cavoatrial junction or lower superior vena cava 3) In the subclavian vein near the clavicle 4) In the axillary vein
Correct Answer: At the cavoatrial junction or lower superior vena cava
Explanation: For upper-body central devices, the desired tip location is generally the lower superior vena cava near the cavoatrial junction. This provides high blood �ow for rapid dilution while avoiding a tip that is too proximal or excessively deep in the heart.Page 3