CITI Human Subjects Research Certification Practice Test 50 Questions

CITI HUMAN SUBJECTS

RESEARCH

CERTIFICATION PRACTICE

TEST 50 QUESTIONS

Question 1: Which Belmont Report principle is most directly supported by giving a capable adult meaningful information and allowing a voluntary decision about research participation?

Choices:

1) Respect for persons 2) Bene�cence 3) Justice 4) Scienti�c validity

Correct Answer: Respect for persons

Explanation: Respect for persons recognizes autonomy and requires that capable individuals be given adequate information and a voluntary opportunity to decide whether to participate.Page 1

Question 2: A research team redesigns a blood-draw schedule so that the same

scienti�c objective can be met with fewer venipunctures. Which ethical principle is most directly re�ected?

Choices:

1) Justice 2) Bene�cence 3) Respect for persons 4) Transparency

Correct Answer: Bene�cence

Explanation: Bene�cence requires researchers to minimize possible harms and maximize possible bene�ts. Reducing unnecessary procedures lowers research risk without sacri�cing the study objective.Question 3: An investigator recruits only economically disadvantaged patients for a burdensome study mainly because they are easy to access, even though the research question does not require that population. Which Belmont principle is most clearly implicated?

Choices:

1) Respect for persons 2) Bene�cence 3) Justice 4) Fidelity

Correct Answer: Justice

Explanation: Justice concerns the fair distribution of research burdens and bene�ts. Selecting a disadvantaged group merely for convenience can impose burdens inequitably.Page 2

Question 4: Which historical development most directly created the National

Commission that later issued the Belmont Report?

Choices:

1) The National Research Act of 1974 2) The HIPAA Privacy Rule 3) The Kefauver-Harris Amendments 4) The Declaration of Helsinki alone

Correct Answer: The National Research Act of 1974

Explanation: The National Research Act of 1974 established the National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research, which later issued the Belmont Report.

Question 5: Which ethical requirement is most closely associated with the

Nuremberg Code?

Choices:

1) Mandatory payment to all subjects 2) Voluntary consent of the human subject 3) Use of placebo controls in every trial 4) Annual IRB review of all research

Correct Answer: Voluntary consent of the human subject

Explanation: The Nuremberg Code prominently established voluntary consent as a

foundational requirement for ethical research involving human participants.Page 3