CERTIFIED PROFESSIONAL
IN IACUC
ADMINISTRATION CPIA
PRACTICE EXAM
COMPLETE
Question 1: Which federal o�ce is responsible for the general administration and coordination of the Public Health Service Policy on Humane Care and Use of Laboratory Animals?
Choices:
1) O�ce of Laboratory Animal Welfare 2) USDA Animal Care 3) Food and Drug Administration Center for Veterinary Medicine 4) AAALAC International
Correct Answer: O�ce of Laboratory Animal Welfare
Explanation: The O�ce of Laboratory Animal Welfare (OLAW), within NIH, administers and coordinates the PHS Policy. USDA Animal Care administers the Animal Welfare Act regulations, while AAALAC is an independent accrediting organization.Page 1
Question 2: A research institution receives NIH support for a project using purpose- bred mice. Which oversight framework applies to the live vertebrate animal activity even though purpose-bred mice are excluded from the Animal Welfare Act de�nition of animal?
Choices:
1) Only state veterinary practice law 2) PHS Policy 3) Only the Animal Welfare Act 4) No federal animal-welfare framework applies
Correct Answer: PHS Policy
Explanation: PHS Policy applies to PHS-conducted or supported activities involving live vertebrate animals, including purpose-bred mice. Purpose-bred mice of the genus Mus are excluded from the AWA de�nition of animal, but that does not remove PHS Policy obligations.
Question 3: Which statement best describes AAALAC International accreditation?
Choices:
1) It is a mandatory federal license for every research facility 2) It replaces IACUC review when an institution is accredited 3) It is a voluntary peer-review accreditation of animal care and use programs 4) It is the USDA enforcement process for Animal Welfare Act violations Correct Answer: It is a voluntary peer-review accreditation of animal care and use programs Explanation: AAALAC International provides voluntary accreditation through peer review.Accreditation does not replace applicable laws, PHS Policy requirements, or IACUC oversight.Page 2
Question 4: Which law provided the statutory basis for the modern PHS Policy
requirement that institutions receiving PHS support establish animal care and use oversight?
Choices:
1) Bayh-Dole Act of 1980 2) Federal Food, Drug, and Cosmetic Act of 1938 3) Occupational Safety and Health Act of 1970 4) Health Research Extension Act of 1985
Correct Answer: Health Research Extension Act of 1985
Explanation: The Health Research Extension Act of 1985 established statutory requirements for humane care and use of animals in PHS-supported research and led to the 1986 PHS Policy framework.Question 5: Which historical concept is most directly associated with Replacement, Reduction, and Re�nement in animal research?
Choices:
1) The Three Rs described by Russell and Burch 2) The Belmont principles 3) The Common Rule exemptions 4) The GLP quality-system principles
Correct Answer: The Three Rs described by Russell and Burch
Explanation: Russell and Burch articulated the Three Rs: Replacement, Reduction, and Re�nement. These principles remain central to humane experimental design and IACUC review.Page 3