Question 1
Which of the following is commonly prescribed for treatment of hypokalemia?
Correct Answer:
Oral potassium
Explanation:
Correct answer: Oral potassium
Question 2
A 62-year-old female presents with fatigue and pruritus. Labs reveal elevated alkaline phosphatase and mild bilirubin elevation. Imaging rules out biliary obstruction. Over time, she develops hyperlipidemia and xanthomas. Although this is a hepatobiliary disease, patients can also present with renal tubular acidosis. Which disease?
Correct Answer:
Primary biliary cholangitis (PBC)
Explanation:
Correct answer: Primary biliary cholangitis (PBC)
Question 3
A patient in the intensive care unit has a fractional excretion of sodium (FeNa) 20:1). Which type of acute kidney injury does this indicate?
Correct Answer:
Prerenal azotemia
Explanation:
Correct answer: Prerenal azotemia
Question 4
A 45-year-old male with hematuria has bilateral flank masses palpable on exam. Imaging reveals enlarged cystic kidneys. Which extrarenal manifestation is commonly associated with this condition?
Correct Answer:
Cerebral “berry” aneurysms
Explanation:
Correct answer: Cerebral “berry” aneurysms
Question 5
A 25-year-old male presents with severe right flank pain radiating to the groin, nausea, and hematuria. Which imaging modality is most appropriate first-line to evaluate suspected nephrolithiasis?
Correct Answer:
Noncontrast CT scan of the abdomen/pelvis
Explanation:
Correct answer: Noncontrast CT scan of the abdomen/pelvis
Question 1
Exam overview

About this Exam

The PANCE (Physician Assistant National Certifying Examination) is the essential licensure exam that all graduates of accredited physician assistant programs in the United States must pass to become a certified Physician Assistant (PA-C). This comprehensive exam assesses a candidate's medical and surgical knowledge, ensuring they possess the core competencies required for safe and effective practice. For those specializing or needing to bolster their understanding of the urinary tract and kidney function, a focused study of the renal system is critical, as this subject matter represents a significant portion of the general medicine topics covered on the exam.

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What the Course Entails and Exam Details

The Renal System section of the PANCE covers a wide spectrum of nephrology and urology topics. Preparation for this section entails a deep understanding of glomerular diseases, acute kidney injury (AKI), chronic kidney disease (CKD), fluid and electrolyte acid-base disorders, and various tubulointerstitial diseases. It also includes common urological conditions such as urinary tract infections, kidney stones, and lower urinary tract symptoms. Students are expected to understand the pathophysiology, clinical presentation, diagnostic approach (including lab interpretation and imaging), and management strategies for these conditions.


What to Expect in the Final Exam

The PANCE is a computer-based, multiple-choice exam consisting of 300 questions administered in five blocks of 60 questions each. Candidates are given a total of five hours to complete the exam, with allotted break times between blocks. The questions are primarily clinical vignettes, requiring the application of medical knowledge to patient scenarios. The passing score is determined by the National Commission on Certification of Physician Assistants (NCCPA) using a criterion-referenced method, ensuring that all candidates are measured against a standard of minimal competence. It is essential to manage time effectively and practice with standardized questions.


How to Study and Exam Centers

To effectively study for the PANCE Renal System section, candidates should utilize the official NCCPA content blueprint as their primary guide. Recommended strategies include utilizing comprehensive PA review books, reviewing medical textbooks focused on internal medicine and nephrology, and completing numerous practice questions from reputable question banks (Qbanks). Forming study groups and attending PANCE review courses can also provide structured support. The PANCE is administered year-round at Pearson VUE testing centers located across the country. Candidates must register through the NCCPA website to schedule their exam date and location.


Job Opportunities from the Course

Achieving PANCE certification is the key to unlocking the full spectrum of career opportunities available to Physician Assistants. This credential allows PAs to practice medicine in virtually every specialty and setting.

Some of the primary career paths include:

  • Licensed Physician Assistant (PA-C) in Primary Care/Family Medicine

  • Nephrology Physician Assistant

  • Urology Physician Assistant

  • Hospitalist Physician Assistant

  • Emergency Medicine Physician Assistant

  • Internal Medicine Specialist PA

  • Surgical Subspecialty PA (e.g., Transplant Surgery)

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