Question 1
Asbestosis is classically associated with which exposure and finding?
Correct Answer:
Ships, insulation exposure with pleural plaques
Explanation:
Asbestos exposure causes chronic lung disease that often shows both interstitial fibrosis (asbestosis) and pleural involvement. The classic setting is work with ships and insulation, where asbestos was heavily used. Pleural plaques—calcified fibrous thickenings on the diaphragmatic or lateral pleura—are a hallmark imaging finding associated with prior asbestos exposure. They can occur with or without significant lung fibrosis and are strong evidence of past exposure. Coal mining causes coal workers’ pneumoconiosis with nodules and progressive fibrosis, not the pleural plaques typical of asbestos. Sandblasting can expose to silica, leading to silicosis with upper-lobe nodules and eggshell calcifications, not the pleural plaques typical of asbestos. Welding fumes may cause metal-related lung changes but are not the classic source of pleural plaques. Therefore, exposure to ships and insulation with pleural plaques best fits as the asbestos-associated pattern.
Question 2
Which statement about Homan's sign for DVT is most accurate?
Correct Answer:
It is unreliable for DVT assessment
Explanation:
Homan's sign is not a reliable indicator for DVT. The test—holding the foot in dorsiflexion to elicit calf pain—has very limited sensitivity and specificity, so a positive or negative result does not meaningfully change the probability of DVT. Calf pain can arise from many other causes (muscle strain, cellulitis, irritation of the Achilles or soleus area, etc.), and some patients with DVT may not have this sign at all. Because of this poor diagnostic value, a positive Homan sign does not confirm DVT, and a negative sign does not rule it out. In practice, diagnosis relies on imaging with compression ultrasonography (and, in low-risk patients, D-dimer to help triage), rather than on Homan's sign.
Question 3
Which statement about TB IGRA interpretation is true?
Correct Answer:
IGRA interpretation cannot differentiate active from latent TB.
Explanation:
TB IGRA tests measure T-cell release of interferon-gamma in response to TB-specific antigens, which indicates infection with Mycobacterium tuberculosis but does not reveal whether the infection is active or latent. That limitation is why this statement is true: the test cannot differentiate active TB from latent TB based on IGRA results alone. IGRA's specificity is higher in BCG-vaccinated individuals because the antigens used are not present in BCG strains, so prior vaccination does not cause a false-positive IGRA. However, you still determine active disease through clinical evaluation, chest imaging, and microbiologic confirmation, since IGRA cannot distinguish disease activity.
Question 4
In sarcoidosis, which radiographic finding is NOT typical?
Correct Answer:
Noncaseating granulomas (histology)
Explanation:
The key idea is that chest imaging in sarcoidosis typically shows signs of lymph node involvement and interstitial lung changes—not tissue-level histology. On radiographs, you’d expect bilateral hilar lymphadenopathy and a reticulonodular pattern from granulomatous infiltration in the lungs. Cavitary lesions are not a typical radiographic feature of sarcoidosis, and when present they raise other possibilities. The histologic hallmark of sarcoidosis is noncaseating granulomas, which are a tissue finding seen on biopsy, not something seen on a chest X-ray. Because the question asks for a radiographic finding, the noncaseating granulomas described histologically are not a radiographic feature, making that option the correct choice.
Question 5
Which finding is most indicative of asthma when evaluating airway reversibility?
Correct Answer:
Reversibility with bronchodilators
Explanation:
Reversibility after a bronchodilator is the hallmark feature that points to asthma. In asthma, the airways are inflamed and hyperresponsive, so they often dilate noticeably after inhaled bronchodilators, which shows up as an improvement in spirometry, especially the FEV1. A common teaching threshold is an increase in FEV1 of about 12% and at least 200 mL from baseline within minutes after a short-acting bronchodilator. This pattern helps distinguish asthma from more fixed obstructive conditions, where the bronchodilator effect is minimal or absent. The other scenarios don’t fit as well. No response to bronchodilators argues against asthma rather than for it, and a chronic dry cough without wheeze or being over 70 years old are nonspecific and can occur with many other conditions. So, observing a clear bronchodilator-induced improvement in airway function best indicates asthma.
Question 1
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Prepare with the PANCE Pulmonology Practice Test practice quiz. This question bank includes 10 questions covering finding, asthma, associated, symptoms, and pance. Use it to review important concepts, identify knowledge gaps, and build confidence for the related exam, course, or assessment.

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PANCE Pulmonology Practice Test

This practice set contains 10 questions from the matching question bank and focuses on finding, asthma, associated, symptoms, and pance. Work through each question carefully, review the provided solutions, and revisit topics that need more study before your next attempt.

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