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Question 1
Which antibiotic is supplied by Cathay Drug?
Correct Answer:
Benzylpenicillin
Explanation:
The question tests familiarity with which antibiotic a supplier stocks. Cathay Drug is known in many practice references for supplying benzylpenicillin (penicillin G) preparations for injection. Among the options, this is the classic injectable penicillin that matches Cathay Drug’s product line. The other drugs belong to different families or forms—cloxacillin is a penicillinase-resistant penicillin, amoxicillin is an oral amino-penicillin, and cefaclor is a cephalosporin—so they don’t align with Cathay Drug’s typical listing.
Question 2
In the well-stirred model, holding Clint and fu constant, what happens to CLh as hepatic blood flow Qh increases?
Correct Answer:
CLh increases
Explanation:
In the well-stirred liver model, hepatic clearance depends on both blood flow to the liver and the liver’s intrinsic ability to clear the drug. The relationship is given by CLh = Qh × (fu × Clint) / (Qh + fu × Clint). If Clint and fu are held constant, CLh changes with Qh in a saturating way. When Qh is small, CLh grows roughly in proportion to Qh. As Qh increases and becomes large compared to fu × Clint, CLh approaches fu × Clint and levels off. So increasing hepatic blood flow raises CLh, up to a maximum set by the intrinsic clearance.
Question 3
Which antibiotic is a beta-lactam antibiotic combined with clavulanic acid?
Correct Answer:
Amoxicillin + Clavulanic acid
Explanation:
Clavulanic acid acts as a beta-lactamase inhibitor, meaning it blocks the enzymes some bacteria produce that would destroy a beta-lactam antibiotic. When you pair a beta-lactam antibiotic like amoxicillin with clavulanic acid, the combination is protected from those enzymes, so the drug can work against a broader range of organisms that would otherwise inactivate it. That’s why the product you’re looking for is amoxicillin combined with clavulanic acid, often sold as Co-amoxiclav. This pairing enhances effectiveness against beta-lactamase–producing bacteria. Amoxicillin by itself is just a beta-lactam antibiotic without the inhibitor, and rifampicin is a different class altogether.
Question 4
What is the effect of increasing the unbound fraction (fu) on clearance and free drug exposure?
Correct Answer:
Increases both clearance and free exposure
Explanation:
Unbound fraction tells us how much drug is available for clearance and for pharmacologic action. In the liver, as the fraction unbound increases, more drug is accessible to metabolic enzymes, so clearance rises. The relationship is often described by the well-stirred model, where increasing fu pushes clearance upward toward the liver’s blood-flow limit. At the same time, the portion that is unbound in plasma also increases, so the free drug concentration (and thus free exposure) goes up. Although total exposure may change as clearance changes, the unbound exposure itself increases with fu. That’s why increasing the unbound fraction raises both clearance and free exposure.
Question 5
Cefixime is supplied by UAP under which brand name?
Correct Answer:
Tergecef
Explanation:
Brand naming of antibiotics varies by manufacturer, so you need to know which brand a company markets for a given generic. For cefixime, UAP lists it under the brand Tergecef. This is the brand you’d encounter from that company’s cefixime product. The other options are different antibiotics or brands not associated with UAP’s cefixime, so they don’t match the product described. In exams like this, matching the generic drug to the specific brand used by a company helps you identify the exact product quickly.
Question 1
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Prepare with the MDC Pharmacokinetics (PK) II Practice Exam practice quiz. This question bank includes 10 questions covering drug, antibiotic, clearance, supplied, and happens. Use it to review important concepts, identify knowledge gaps, and build confidence for the related exam, course, or assessment.

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MDC Pharmacokinetics (PK) II Practice Exam

This practice set contains 10 questions from the matching question bank and focuses on drug, antibiotic, clearance, supplied, and happens. Work through each question carefully, review the provided solutions, and revisit topics that need more study before your next attempt.

This is an independent study resource intended for practice and review; it is not an official examination or an endorsement by any organization named in the title.

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