Question 1
A 62-year-old patient with type 2 diabetes and an eGFR of 25 mL/min/1.73m² is currently taking metformin 1g twice daily. According to NICE guidelines, what action should be recommended?
Correct Answer:
Discontinue metformin as eGFR is below 30 mL/min/1.73m²
Question 2
A patient is started on ramipril for hypertension. After two weeks, blood tests show a rise in serum creatinine of 35% from baseline. What is the most appropriate action?
Correct Answer:
Stop ramipril immediately and investigate for renal artery stenosis
Question 3
Which antibiotic is recommended as first-line treatment for an uncomplicated lower urinary tract infection in a non-pregnant adult woman, according to NICE guidelines?
Correct Answer:
Nitrofurantoin 100mg modified-release twice daily for 3 days
Question 4
A patient on long-term oral corticosteroids (prednisolone 15mg daily for 6 months) wants to stop the medication. What is the recommended approach?
Correct Answer:
Gradually taper the dose to avoid adrenal crisis
Question 5
A 70-year-old patient with atrial fibrillation has a CHA₂DS₂-VASc score of 4. Which of the following is the most appropriate anticoagulation strategy according to NICE?
Correct Answer:
A direct oral anticoagulant (DOAC) such as apixaban or edoxaban
Question 1
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Prepare with the GPhC Registration Assessment practice quiz. This question bank includes 160 questions covering patient, prescription, pharmacist, drug, and nice. Use it to review important concepts, identify knowledge gaps, and build confidence for the related exam, course, or assessment.

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GPhC Registration Assessment

This practice set contains 160 questions from the matching question bank and focuses on patient, prescription, pharmacist, drug, and nice. Work through each question carefully, review the provided solutions, and revisit topics that need more study before your next attempt.

This is an independent study resource intended for practice and review; it is not an official examination or an endorsement by any organization named in the title.

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