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Question 1
Latanoprost's effect on the pupil in lens instability is to cause which change?
Correct Answer:
Miosis
Explanation:
Latanoprost is a prostaglandin F2α analog used to lower intraocular pressure by increasing uveoscleral outflow, but it can also influence the iris by modestly affecting the tone of iris smooth muscle. In the context of lens instability, a smaller pupil tends to stabilize the iris-lens diaphragm and reduce anterior movement of the lens, which can help minimize lens-capsule movement during accommodation or changes in gaze. Therefore, latanoprost can lead to pupil constriction (miosis), making this the expected effect. Pupillary atony would imply loss of iris sphincter function, which is not how latanoprost acts. No pupil change would ignore the potential influence on iris tone, and mydriasis (pupil dilation) would worsen lens instability by allowing more movement. Hence, the best answer is miosis.
Question 2
What dangerous event can occur if the pupil dilates in a subluxated lens?
Correct Answer:
Anterior luxation
Explanation:
In a subluxated lens, the zonules holding the lens in place are weak, so the lens position is unstable. When the pupil dilates, the iris moves away and the lens-iris diaphragm can shift forward. This forward movement can push the lens into the anterior chamber, causing pupillary-block–type glaucoma and a dangerous rise in intraocular pressure. That acute forward displacement into the front of the eye is the dangerous event most likely to occur with dilation. Moving the lens backward into the vitreous isn’t as immediately perilous in this scenario, and cataract formation or retinal detachment aren’t acute effects triggered by pupil dilation.
Question 3
What type of LIU is due to capsule rupture?
Correct Answer:
Phacoclastic uveitis
Explanation:
Phacoclastic uveitis occurs when the lens capsule ruptures, releasing the entire lens contents into the anterior chamber. That abrupt exposure of highly antigenic lens proteins triggers a robust inflammatory response in the uveal tissues, often presenting acutely after trauma or a rupture during surgery. This distinguishes it from phacolytic uveitis, which happens with an intact capsule in a hypermature lens where leaked soluble proteins slowly provoke inflammation. Iris bombe is not driven by lens protein leakage at all; it’s a pupillary block mechanism causing anterior chamber shallowing and iris bowing. Chronic anterior uveitis refers to long-standing inflammation of the anterior uveal tract, not specifically linked to capsule rupture.
Question 4
Scleral-fixated intraocular lens is indicated under which condition?
Correct Answer:
When there is insufficient capsular support due to zonular weakness or rupture
Explanation:
Scleral-fixated intraocular lenses are used when the eye cannot support a lens in the natural bag because the capsule or the zonules are damaged or missing. When capsular support is insufficient due to zonular weakness or rupture, the lens can’t be placed securely in the lens capsule, so fixing it to the sclera provides stable, pseudo–posterior-chamber support. That’s why this is the best indication. If there is intact capsular support, the standard in-the-bag placement is preferred. Corneal scarring doesn’t dictate scleral fixation, and while a shallow anterior chamber depth influences lens choice, it isn’t the primary indication for scleral fixation.
Question 5
Where do new lens fibers form?
Correct Answer:
At the equator of the lens
Explanation:
New lens fibers form at the equator because this is the germinative zone where the anterior lens epithelium proliferates and then differentiates into elongated fiber cells. These differentiating fibers add to the existing lens by expanding outward from the equator and then stretching inward toward the center, gradually increasing the lens size. The central nucleus is made of fibers formed earlier in development and remains relatively constant in adulthood, while the posterior pole and the anterior capsule do not serve as sites of new fiber formation.
Question 1
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About this Exam

Prepare with the Disorders of the Lens Practice Test practice quiz. This question bank includes 10 questions covering lens, pupil, capsule, cataract, and disorders. Use it to review important concepts, identify knowledge gaps, and build confidence for the related exam, course, or assessment.

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Disorders of the Lens Practice Test

This practice set contains 10 questions from the matching question bank and focuses on lens, pupil, capsule, cataract, and disorders. Work through each question carefully, review the provided solutions, and revisit topics that need more study before your next attempt.

This is an independent study resource intended for practice and review; it is not an official examination or an endorsement by any organization named in the title.

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