Question 1
A couple presents for genetic counseling after their first child was diagnosed with cystic fibrosis. Both parents are confirmed carriers of the CFTR p.Phe508del variant. What is the recurrence risk for each subsequent pregnancy?
Correct Answer:
25%
Question 2
Which ACMG variant classification category is assigned to a variant with strong evidence of pathogenicity but insufficient to meet criteria for Pathogenic?
Correct Answer:
Likely pathogenic
Question 3
A woman at 11 weeks gestation undergoes chorionic villus sampling (CVS). The laboratory reports mosaic trisomy 16, raising concern for confined placental mosaicism. What is the most appropriate next step?
Correct Answer:
Offer amniocentesis for fetal assessment
Question 4
In Hardy-Weinberg equilibrium, if the frequency of a recessive disease allele (q) is 0.01, what is the expected carrier frequency in the population?
Correct Answer:
About 1.98%
Question 5
A 35-year-old woman with a BRCA1 pathogenic variant asks when annual contrast-enhanced breast MRI generally begins. What is the guideline-based starting age?
Correct Answer:
Age 25
Question 1
Exam overview

About this Exam

Prepare with the CGC Practice Questions - ABGC Certified Genetic Counselor Exam practice quiz. This question bank includes 100 questions covering genetic, variant, syndrome, testing, and child. Use it to review important concepts, identify knowledge gaps, and build confidence for the related exam, course, or assessment.

More details

Additional Information

CGC Practice Questions - ABGC Certified Genetic Counselor Exam

This practice set contains 100 questions from the matching question bank and focuses on genetic, variant, syndrome, testing, and child. Work through each question carefully, review the provided solutions, and revisit topics that need more study before your next attempt.

This is an independent study resource intended for practice and review; it is not an official examination or an endorsement by any organization named in the title.

Quiz information

Frequently Asked Questions

The complete question count is available after full access is unlocked.
No fixed duration is currently configured for this quiz.
Question explanations are included where they are available in the quiz content, helping you review the reasoning after answering.
Yes. You can retake the practice test again as you continue studying during your available access period.
After your access is confirmed, you can continue into the complete practice exam from this quiz flow.
Unless explicitly stated otherwise, this page provides independent practice material for study and exam preparation and is not the official examination itself.
Keep studying

Related Questions