Question 1
A 65-year-old has a peripheral blood smear showing smudge cells and small mature lymphocytes with scant cytoplasm and clumped chromatin. Flow cytometry: CD19+, CD5+, CD23+, CD20 dim, kappa/lambda light chain restricted. Diagnosis?
Correct Answer:
Chronic lymphocytic leukemia (CLL)
Question 2
A 35-year-old woman has microcytic anemia (Hb 9.5 g/dL, MCV 68 fL). Iron studies show low serum iron, low ferritin, high TIBC, and low transferrin saturation (
Correct Answer:
Iron deficiency anemia
Question 3
Hemoglobin electrophoresis on a Black patient with microcytic anemia shows HbA 85%, HbA2 5.5%, HbF 2%. Diagnosis?
Correct Answer:
Beta-thalassemia minor (trait)
Question 4
A peripheral smear shows schistocytes, platelets
Correct Answer:
Thrombotic thrombocytopenic purpura (TTP)
Question 5
A patient on IV heparin develops a platelet count drop from 250 to 85 × 10⁹/L after 7 days with new DVT. 4Ts score is 7. Which HIT test should be ordered first?
Correct Answer:
Heparin-platelet factor 4 (PF4) ELISA (anti-PF4/heparin antibodies) as screening, followed by serotonin release assay (SRA) if positive/intermediate
Question 1
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About this Exam

Prepare with the ABPath Clinical Pathology Practice Questions - American Board of Pathology Clinical Pathology Primary Certification Examination Exam practice quiz. This question bank includes 100 questions covering patient, shows, diagnosis, transfusion, and year-old. Use it to review important concepts, identify knowledge gaps, and build confidence for the related exam, course, or assessment.

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ABPath Clinical Pathology Practice Questions - American Board of Pathology Clinical Pathology Primary Certification Examination Exam

This practice set contains 100 questions from the matching question bank and focuses on patient, shows, diagnosis, transfusion, and year-old. Work through each question carefully, review the provided solutions, and revisit topics that need more study before your next attempt.

This is an independent study resource intended for practice and review; it is not an official examination or an endorsement by any organization named in the title.

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