Question 1
A 62-year-old man presents to the emergency department 75 minutes after the sudden onset of right hemiparesis and global aphasia. His baseline modified Rankin Scale (mRS) is 0. Non-contrast cranial computed tomography (CT) reveals an ASPECTS score of 9 with no acute hemorrhage or early ischemic changes. His blood pressure is 172/96 mmHg, blood glucose is 134 mg/dL, and international normalized ratio (INR) is 1.0. According to current Brazilian and international acute ischemic stroke guidelines, what is the most appropriate immediate medical intervention?
Correct Answer:
Initiate intravenous thrombolysis with recombinant tissue plasminogen activator (Alteplase 0.9 mg/kg or Tenecteplase 0.25 mg/kg) without waiting for further imaging.
Question 2
A 68-year-old woman was last seen well at 10:00 PM when going to bed. At 7:00 AM the next morning (9 hours later), her family finds her with dense left-sided hemiplegia and neglect (NIHSS score of 17). Non-contrast cranial CT reveals no intracranial hemorrhage and an ASPECTS score of 8. CT angiography confirms an occlusion of the M1 segment of the right middle cerebral artery. Perfusion CT demonstrates an ischemic core volume of 18 mL and a total hypoperfused penumbral volume of 94 mL (mismatch volume of 76 mL; mismatch ratio > 5.0). Based on the DAWN and DEFUSE-3 clinical trial criteria, what is the indicated management?
Correct Answer:
Immediate mechanical thrombectomy with a stent retriever and/or contact aspiration.
Question 3
A 55-year-old man with uncontrolled hypertension presents with sudden severe headache, vomiting, and right hemiplegia. Cranial CT reveals a 35 mL spontaneous intracerebral hemorrhage (ICH) centered in the left putamen with mild surrounding edema and intraventricular extension into the left lateral ventricle. His initial Glasgow Coma Scale (GCS) score is 11, and he is 55 years old (age < 80). His initial blood pressure is 210/115 mmHg. According to the original ICH Score (Hemphill et al.) and acute ICH management guidelines, what is his calculated ICH score and recommended acute target systolic blood pressure?
Correct Answer:
ICH score of 2; target systolic blood pressure rapidly lowered and maintained between 130 and 140 mmHg.
Question 4
A 48-year-old woman presents to the emergency department after experiencing the sudden onset of the 'worst headache of her life' accompanied by neck stiffness and photophobia. Non-contrast cranial CT reveals diffuse hyperdensity in the basal cisterns and Sylvian fissures consistent with acute aneurysmal subarachnoid hemorrhage (aSAH). Digital subtraction angiography identifies a 7 mm saccular aneurysm of the anterior communicating artery. To prevent delayed cerebral ischemia (DCI) and secondary neurological deterioration, which pharmacologic intervention is recommended as Class I evidence?
Correct Answer:
Oral Nimodipine 60 mg every 4 hours for 21 consecutive days.
Question 5
A 29-year-old woman on oral combined contraceptives presents with a 5-day history of progressive headache, nausea, and recent onset of left-sided focal motor seizures with secondary generalization. Cranial MRI and MR venography demonstrate extensive thrombosis of the superior sagittal sinus and right transverse sinus with a small cortical venous hemorrhagic infarction in the right parietal lobe. What is the first-line therapeutic management?
Correct Answer:
Full therapeutic anticoagulation with low-molecular-weight heparin (LMWH) or unfractionated heparin, despite the presence of intracranial hemorrhage.
Question 1
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Prepare with the TEN Neurologia Practice Questions - TEN - Título de Especialista em Neurologia (Academia Brasileira de Neurologia AMB) Exam practice quiz. This question bank includes 100 questions covering year-old, presents, right, reveals, and brain. Use it to review important concepts, identify knowledge gaps, and build confidence for the related exam, course, or assessment.

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TEN Neurologia Practice Questions - TEN - Título de Especialista em Neurologia (Academia Brasileira de Neurologia AMB) Exam

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