Question 1
A 68-year-old man with atrial fibrillation is started on amiodarone. Six weeks later his INR, taken because he is also on warfarin, has risen sharply despite no change in warfarin dose. Which mechanism best explains this interaction?
Correct Answer:
Amiodarone inhibits CYP2C9 and CYP3A4, reducing warfarin metabolism
Question 2
A drug has a half-life of 8 hours and is given by continuous intravenous infusion at a constant rate. Approximately how long will it take to reach steady-state plasma concentration?
Correct Answer:
About 36-40 hours
Question 3
A 24-year-old woman presents 6 hours after taking 30 paracetamol tablets in a single overdose. Her plasma paracetamol concentration is above the treatment line on the nomogram. Which is the most appropriate immediate management?
Correct Answer:
Intravenous N-acetylcysteine
Question 4
Which of the following antihypertensive drugs acts primarily by blocking the conversion of angiotensin I to angiotensin II?
Correct Answer:
Ramipril
Question 5
A patient on long-term lithium for bipolar disorder develops a coarse tremor, ataxia, confusion and a lithium level of 2.4 mmol/L. Which recently added medication is the most likely precipitant?
Correct Answer:
Bendroflumethiazide
Question 1
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Prepare with the MRCP(UK) Part 1 Practice Questions - MRCP(UK) Part 1 Exam practice quiz. This question bank includes 100 questions covering year-old, presents, woman, diagnosis, and shows. Use it to review important concepts, identify knowledge gaps, and build confidence for the related exam, course, or assessment.

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MRCP(UK) Part 1 Practice Questions - MRCP(UK) Part 1 Exam

This practice set contains 100 questions from the matching question bank and focuses on year-old, presents, woman, diagnosis, and shows. Work through each question carefully, review the provided solutions, and revisit topics that need more study before your next attempt.

This is an independent study resource intended for practice and review; it is not an official examination or an endorsement by any organization named in the title.

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