Question 1
A 54-year-old bank executive presents with a 7-week history of profound pervasive low mood, distinct lack of emotional reactivity, waking daily at 03:30 (more than 2 hours before his usual alarm) with severe morning exacerbation of depressive symptoms, psychomotor retardation, marked anorexia with a 6 kg weight loss, and excessive feelings of guilt regarding minor administrative oversights at work. He denies psychotic symptoms. According to ICD-10 (F32.2) and DSM-5 criteria, what is the most accurate diagnostic specification for this episode?
Correct Answer:
Major depressive episode with melancholic features (somatic syndrome)
Question 2
A 42-year-old woman with unipolar major depressive disorder has failed to achieve clinical remission despite sequential 8-week trials of escitalopram (20 mg/day) and venlafaxine extended-release (225 mg/day), both taken with verified therapeutic compliance and confirmed therapeutic plasma levels on therapeutic drug monitoring (TDM). She meets criteria for Treatment-Resistant Depression (TRD). According to Swiss Society of Psychiatry and Psychotherapy (SGPP) and WFSBP guidelines, which evidence-based pharmacological strategy has the highest level of empirical evidence for next-step augmentation?
Correct Answer:
Augmentation with Lithium (target serum trough level 0.6–0.8 mmol/L) or a low-dose second-generation antipsychotic (e.g., aripiprazole)
Question 3
A 38-year-old man with treatment-resistant unipolar depression is being evaluated for intranasal esketamine (Spravato) therapy in a Swiss psychiatric outpatient clinic. Which of the following clinical monitoring requirements and Swissmedic-approved administration protocols is mandatory during each treatment session?
Correct Answer:
Direct administration in a certified medical facility under healthcare professional supervision, with mandatory blood pressure monitoring before dosing, at ~40 minutes, and until clinical stability at ~120 minutes post-dose
Question 4
A 29-year-old man is brought to the emergency department by the police after climbing onto the roof of a municipal building in Zurich, shouting that he has been appointed by the federal council to eliminate the national debt. He has slept 1 hour per night for 6 days, speaks with intense pressure, displays racing thoughts and grandiosity, and has spent CHF 45,000 on luxury watches within 48 hours. Physical exam and drug screen are negative. According to SGPP and CANMAT guidelines, what is the most appropriate first-line pharmacotherapeutic approach?
Correct Answer:
Initiate an atypical antipsychotic (e.g., olanzapine, quetiapine, or aripiprazole) either as monotherapy or combined with a mood stabilizer (e.g., lithium or valproate)
Question 5
A 34-year-old woman presents with severe fatigue, profound anhedonia, hypersomnia, and feelings of worthlessness for 4 weeks. Careful psychiatric history reveals two previous distinct 4-day episodes of elevated mood, decreased need for sleep, uncharacteristic talkativeness, and increased goal-directed productivity that did not cause hospitalization or psychotic symptoms. She is diagnosed with Bipolar II disorder, current episode depressed. Which of the following pharmacotherapies has the strongest evidence-based indication as first-line monotherapy for acute bipolar II depression?
Correct Answer:
Quetiapine (300 mg/day)
Question 1
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Prepare with the Facharzt FMH Psychiatrie und Psychotherapie Practice Questions - Facharzt FMH für Psychiatrie und Psychotherapie Spécialiste FMH en psychiatrie et psychothérapie Exam practice quiz. This question bank includes 100 questions covering year-old, severe, disorder, clinical, and woman. Use it to review important concepts, identify knowledge gaps, and build confidence for the related exam, course, or assessment.

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Facharzt FMH Psychiatrie und Psychotherapie Practice Questions - Facharzt FMH für Psychiatrie und Psychotherapie Spécialiste FMH en psychiatrie et psychothérapie Exam

This practice set contains 100 questions from the matching question bank and focuses on year-old, severe, disorder, clinical, and woman. Work through each question carefully, review the provided solutions, and revisit topics that need more study before your next attempt.

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