Question 1
Which fixative is considered the gold standard for routine histology because it provides excellent nuclear detail and is compatible with most special stains?
Correct Answer:
10% neutral buffered formalin (NBF)
Question 2
What is the primary mechanism by which formaldehyde fixes tissue?
Correct Answer:
Formation of cross-links between amino acid residues
Question 3
Which of the following fixatives is classified as a coagulant fixative?
Correct Answer:
Ethanol
Question 4
What artifact is commonly seen in tissues fixed in unbuffered formalin due to the breakdown of formaldehyde in the presence of hemoglobin?
Correct Answer:
Formalin pigment (hematin)
Question 5
What is the optimal fixation time for most surgical specimens in 10% neutral buffered formalin at room temperature?
Correct Answer:
24 to 48 hours
Question 1
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About this Exam

Prepare with the ASCP HTL Practice Questions - Scientist in Histotechnology (HTL) Exam practice quiz. This question bank includes 100 questions covering tissue, fixative, sections, paraffin, and processing. Use it to review important concepts, identify knowledge gaps, and build confidence for the related exam, course, or assessment.

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ASCP HTL Practice Questions - Scientist in Histotechnology (HTL) Exam

This practice set contains 100 questions from the matching question bank and focuses on tissue, fixative, sections, paraffin, and processing. Work through each question carefully, review the provided solutions, and revisit topics that need more study before your next attempt.

This is an independent study resource intended for practice and review; it is not an official examination or an endorsement by any organization named in the title.

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