Question 1
A 58-year-old woman with chronic GERD has an endoscopic biopsy showing columnar epithelium with goblet cells in the distal esophagus. Which of the following best characterizes this lesion?
Correct Answer:
Barrett esophagus (intestinal metaplasia)
Question 2
A colon biopsy from a patient with bloody diarrhea shows continuous mucosal inflammation extending from the rectum proximally, crypt abscesses, and no granulomas. The most likely diagnosis is:
Correct Answer:
Ulcerative colitis
Question 3
A breast biopsy shows nests of cells with low-grade nuclei, monomorphic appearance, and loss of E-cadherin expression by immunohistochemistry. Which diagnosis fits best?
Correct Answer:
Invasive lobular carcinoma
Question 4
A prostate needle biopsy shows fused glands with poorly formed lumens. The pathologist assigns Gleason pattern 4 to all of the tumor. Per the 2014 ISUP/2016 WHO grade group system, this corresponds to:
Correct Answer:
Grade Group 4 (Gleason 4+4=8)
Question 5
A skin biopsy shows a melanocytic lesion with Breslow thickness 2.3 mm, ulceration, and 4 mitoses/mm^2. What is the most appropriate next step in management based on these findings?
Correct Answer:
Wide local excision with consideration of sentinel lymph node biopsy
Question 1
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Prepare with the AOBPa Pathology Practice Questions - AOBPa Pathology Certifying Examination Exam practice quiz. This question bank includes 100 questions covering shows, biopsy, diagnosis, cells, and showing. Use it to review important concepts, identify knowledge gaps, and build confidence for the related exam, course, or assessment.

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AOBPa Pathology Practice Questions - AOBPa Pathology Certifying Examination Exam

This practice set contains 100 questions from the matching question bank and focuses on shows, biopsy, diagnosis, cells, and showing. Work through each question carefully, review the provided solutions, and revisit topics that need more study before your next attempt.

This is an independent study resource intended for practice and review; it is not an official examination or an endorsement by any organization named in the title.

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