Question 1
A 58-year-old woman has a 1.4 cm breast mass. Core biopsy shows invasive carcinoma with tumor cells in single-file and targetoid patterns. E-cadherin immunostain is negative. Which diagnosis is most likely?
Correct Answer:
Invasive lobular carcinoma
Question 2
On core biopsy, a breast lesion demonstrates low-grade nuclei arranged in cribriform and micropapillary architecture confined within duct walls with intact myoepithelium on p63 and calponin. There is no invasion. This is:
Correct Answer:
DCIS, low grade
Question 3
A triple-negative breast carcinoma (ER-/PR-/HER2-) in a 42-year-old woman is most likely associated with which germline mutation?
Correct Answer:
BRCA1
Question 4
Which HER2 IHC score definitively requires reflex in situ hybridization for HER2 status per ASCO/CAP 2023 guidelines?
Correct Answer:
2+
Question 5
A 14-year-old girl has a well-circumscribed, mobile breast mass. Histology shows stromal and epithelial proliferation with intracanalicular and pericanalicular patterns. Mitoses are rare. The best diagnosis is:
Correct Answer:
Fibroadenoma
Question 1
Exam overview

About this Exam

Prepare with the ABPath Anatomic Pathology Practice Questions - American Board of Pathology Anatomic Pathology Primary Certification Examination Exam practice quiz. This question bank includes 100 questions covering shows, year-old, diagnosis, cells, and tumor. Use it to review important concepts, identify knowledge gaps, and build confidence for the related exam, course, or assessment.

More details

Additional Information

ABPath Anatomic Pathology Practice Questions - American Board of Pathology Anatomic Pathology Primary Certification Examination Exam

This practice set contains 100 questions from the matching question bank and focuses on shows, year-old, diagnosis, cells, and tumor. Work through each question carefully, review the provided solutions, and revisit topics that need more study before your next attempt.

This is an independent study resource intended for practice and review; it is not an official examination or an endorsement by any organization named in the title.

Quiz information

Frequently Asked Questions

The complete question count is available after full access is unlocked.
No fixed duration is currently configured for this quiz.
Question explanations are included where they are available in the quiz content, helping you review the reasoning after answering.
Yes. You can retake the practice test again as you continue studying during your available access period.
After your access is confirmed, you can continue into the complete practice exam from this quiz flow.
Unless explicitly stated otherwise, this page provides independent practice material for study and exam preparation and is not the official examination itself.
Keep studying

Related Questions