ABP Pediatric Endocrinology Practice Questions - ABP Pediatric Endocrinology Subspecialty Certification Examination Exam - ABP Pediatric Endocrinology Practice Questions - ABP Pediatric Endocrinology Subspecialty Certification Examination Exam

Question 1

A 9-year-old presents with polyuria, polydipsia, and 5 kg weight loss over 3 weeks. Glucose is 412 mg/dL, pH 7.18, HCO3 10, ketones large, and islet autoantibodies are positive for GAD65, IA2, and ZnT8. Which statement best characterizes the immunologic basis of this disease?

Amyloid deposition within islets impairing insulin secretion Autoantibody-mediated complement lysis of beta cells T-cell mediated autoimmune destruction of pancreatic beta cells, with autoantibodies serving as disease markers rather than the primary effectors Congenital agenesis of the dorsal pancreatic anlage

Correct Answer:

T-cell mediated autoimmune destruction of pancreatic beta cells, with autoantibodies serving as disease markers rather than the primary effectors

Question 2

A 12-year-old with newly diagnosed T1DM is discharged on a basal-bolus regimen. Which insulin pairing correctly represents a modern MDI regimen?

Detemir plus regular insulin as needed for hyperglycemia only NPH twice daily plus regular insulin at meals Glargine plus NPH at bedtime Glargine or detemir once/twice daily plus aspart, lispro, or glulisine at meals

Correct Answer:

Glargine or detemir once/twice daily plus aspart, lispro, or glulisine at meals

Question 3

Which statement about the 'honeymoon phase' of type 1 diabetes is most accurate?

It represents transient partial beta-cell recovery after diagnosis, during which insulin requirements fall below 0.5 U/kg/day It is permanent and indicates spontaneous cure of T1DM It occurs only in adults with latent autoimmune diabetes It is characterized by complete loss of endogenous C-peptide

Correct Answer:

It represents transient partial beta-cell recovery after diagnosis, during which insulin requirements fall below 0.5 U/kg/day

Question 4

A 7-year-old in DKA presents with glucose 520 mg/dL, pH 7.05, HCO3 6, Na 132, K 5.4, and BUN 28. Per ISPAD/PES guidelines, which initial fluid strategy is most appropriate?

10 mL/kg isotonic saline bolus over 30-60 minutes if needed, then replace deficit over 24-48 hours with maintenance; avoid cumulative fluids >40 mL/kg in the first 4 hours Aggressive 40 mL/kg bolus over 1 hour followed by D5 half-normal saline at 2x maintenance Fluid restriction to two-thirds maintenance to prevent cerebral edema Bolus with D10 half-normal saline to treat hyperglycemia

Correct Answer:

10 mL/kg isotonic saline bolus over 30-60 minutes if needed, then replace deficit over 24-48 hours with maintenance; avoid cumulative fluids >40 mL/kg in the first 4 hours

Question 5

In pediatric DKA management, what is the recommended insulin infusion rate and the rationale for avoiding an initial insulin bolus?

0.01 U/kg/hr infusion with no dose adjustment until ketosis resolves 0.3 U/kg bolus followed by 0.3 U/kg/hr infusion to rapidly normalize glucose 0.05-0.1 U/kg/hr continuous; avoid bolus because it does not improve outcomes and increases risk of hypokalemia and rapid osmolar shifts Subcutaneous rapid-acting insulin every 2 hours with no continuous infusion

Correct Answer:

0.05-0.1 U/kg/hr continuous; avoid bolus because it does not improve outcomes and increases risk of hypokalemia and rapid osmolar shifts

Question 1

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Prepare with the ABP Pediatric Endocrinology Practice Questions - ABP Pediatric Endocrinology Subspecialty Certification Examination Exam practice quiz. This question bank includes 100 questions covering year-old, presents, elevated, normal, and girl. Use it to review important concepts, identify knowledge gaps, and build confidence for the related exam, course, or assessment.

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ABP Pediatric Endocrinology Practice Questions - ABP Pediatric Endocrinology Subspecialty Certification Examination Exam

This practice set contains 100 questions from the matching question bank and focuses on year-old, presents, elevated, normal, and girl. Work through each question carefully, review the provided solutions, and revisit topics that need more study before your next attempt.

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ABP Pediatric Endocrinology Practice Questions - ABP Pediatric Endocrinology Subspecialty Certification Examination Exam

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