South California EMS Medical Block Practice Test

Which term describes an allergic reaction mediated by IgE antibodies?

Mild Allergic Reaction IgE-Mediated Reaction Anaphylaxis Signs Severe Allergic Reaction / Anaphylaxis

Correct Answer:

IgE-Mediated Reaction

Explanation:

IgE-mediated reaction describes an allergic response driven by IgE antibodies. In this mechanism, IgE binds to mast cells and basophils; when the allergen reappears, it cross-links those IgE molecules and triggers degranulation, releasing histamine and other mediators that cause the rapid allergy symptoms. The other terms describe how severe the reaction is or reference a clinical syndrome (anaphylaxis) rather than the underlying immunologic pathway, so they don’t specify the mechanism as precisely.

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