CMSA Diploma In Allergology Dip Allerg(SA) Practice Questions - Diploma In Allergology Of The College Of Physicians Of South Africa Dip Allerg(SA) Exam

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Which subunit combination constitutes the high-affinity IgE receptor (FcεRI) expressed on human mast cells and basophils, and which chains contain Immunoreceptor Tyrosine-based Activation Motifs (ITAMs) essential for intracellular signal transduction?
Correct Answer:
Alpha (α) chain, Beta (β) chain, and a disulfide-linked Gamma (γ) homodimer; ITAMs are present on the β and γ chains

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