Singapore GCE A-Level H3 Biology Practice Questions - Singapore GCE A-Level H3 Biology Examination (SEAB Syllabus 9816) Exam

Proto-oncogenes undergo gain-of-function mutations that act dominantly, whereas tumor suppressors undergo loss-of-function mutations that act recessively at the cellular level Proto-oncogenes require loss of both alleles for oncogenesis, whereas tumor suppressors require a mutation in only one allele Proto-oncogenes exclusively encode cytosolic kinases, whereas tumor suppressors encode cell surface receptors Proto-oncogenes promote cell death via apoptosis, whereas tumor suppressors stimulate cell proliferation