EDAPT Intracranial Regulation Practice Test

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Which statement describes a contraindicated administration practice when giving IV diazepam for seizures?
Correct Answer:
Administer into small veins
Explanation:
The main idea here is safe IV administration of diazepam during seizures. Diazepam given IV should be delivered through a sufficiently large vein and at a controlled rate to minimize irritation and potential complications. Administering into small veins is contraindicated because the IV solution contains solvents that can irritate fragile veins. Small veins are more prone to chemical phlebitis, vein inflammation, and tissue damage if extravasation occurs, especially with the propylene glycol solvent used in some IV diazepam formulations. This increases pain, swelling, and the risk of vein injury and complications at the injection site. In contrast, using a larger vein reduces irritation risk, and giving the drug slowly helps prevent respiratory depression and hemodynamic instability. Close monitoring of vital signs is essential during administration, and consulting a drug reference guide can help ensure correct dosing and precautions.

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