Leaving Cert Biology – Genetics Practice Test

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Which statement about sex-linked inheritance is commonly observed in human families?
Correct Answer:
Sex-linked traits are more common in males
Explanation:
Sex-linked inheritance involves genes on the X chromosome. In humans, males have one X and one Y, while females have two Xs. If a gene on the X is recessive, males will express that trait with just one copy because there’s no second X to mask it. Females would need two copies of the recessive allele to show the trait, so X-linked recessive conditions appear much more often in males. This is the reason we commonly observe these traits in males in families, with examples like red-green color blindness or hemophilia. These traits are not autosomal and aren’t inherited only from the mother: fathers pass their X chromosome to daughters, but not to sons, while mothers pass Xs to both sons and daughters.

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