Ambulatory Care Nurse – Board Certified (AMB-BC) Practice Test

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Which statement about NPH insulin is true?
Correct Answer:
It is cloudy
Explanation:
NPH insulin is cloudy because it is prepared as a suspension with protamine, making it an intermediate-acting insulin. The cloudy appearance comes from the suspended particles and you typically roll or gently invert the vial to resuspend before dosing. This suspension-based, intermediate action contrasts with clear, rapid-acting insulins that are solutions. While NPH does provide longer-lasting coverage and has a peak several hours after injection (unlike long-acting analogs that aim for no pronounced peak), it is not guaranteed to last exactly 24 hours in every patient and it is not clear. Therefore, the true statement is that it is cloudy. The other options—being clear, lasting a full 24 hours, or having no peak—do not fit NPH’s characteristics.

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