CMSA FC Path(SA) Anatomical Pathology - South Africa Practice Questions - Fellowship Of The College Of Pathologists Of South Africa - Anatomical Pathology Exam

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Which specific protein is oligomerized during regulated necrosis (necroptosis) to form pore complexes in the plasma membrane, resulting in cell lysis?

Mixed Lineage Kinase Domain-Like Protein (MLKL) Receptor-Interacting Serine/Threonine-Protein Kinase 1 (RIPK1) Caspase-8 Gasdermin D

Correct Answer:

Mixed Lineage Kinase Domain-Like Protein (MLKL)

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