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Associate – Infection Prevention And Control (a-IPC) Practice Exam

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Which serologic marker indicates acute Hepatitis A infection?
Correct Answer:
Anti-HAV IgM
Explanation:
Identifying acute Hepatitis A relies on detecting anti-HAV IgM. This antibody appears early in the course of infection and indicates a recent or active HAV infection, typically appearing with symptoms and then waning over weeks to a few months. In contrast, anti-HAV IgG indicates past exposure or immunity and does not signal active disease. Antibodies to the hepatitis B surface antigen (anti-HBs) reflect immunity to Hepatitis B, usually from vaccination or prior infection, not HAV. The hepatitis B surface antigen (HBsAg) marks current Hepatitis B infection. So, the presence of anti-HAV IgM is the best indicator of an acute Hepatitis A infection.

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