EDAPT Perfusion Practice Test

Facial flushing is a common side effect of niacin due to its pharmacological action. Niacin, also known as vitamin B3, causes the release of prostaglandins, which leads to vasodilation—widening of blood vessels. This vasodilation results in increased blood flow to the skin, especially the face, causing a sensation of warmth and visible redness. This flushing effect can occur shortly after taking niacin and is often accompanied by other sensations such as itching or tingling. While some individuals may find the flushing uncomfortable, it is typically harmless and may diminish over time with continued use or can be managed by adjusting the dose or formulation of niacin. Understanding this side effect is particularly important for patients who are prescribed niacin for lowering cholesterol, as it may impact their adherence to treatment.