Afghanistan Pharmacy Technician Exit Exam Practice Questions - Afghanistan Pharmacy Technician Exit Exam (Institutes Of Health Sciences) Exam

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Which of the following best describes the primary antibacterial mechanism of action of beta-lactam antibiotics such as amoxicillin and penicillin G?

Inhibition of bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs) and blocking peptidoglycan cross-linking Inhibition of the 30S ribosomal subunit preventing bacterial protein translation Inhibition of bacterial DNA gyrase and topoisomerase IV preventing DNA replication Disruption of bacterial cell membrane permeability causing leakage of intracellular ions

Correct Answer:

Inhibition of bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs) and blocking peptidoglycan cross-linking

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