CII Certificate In Insurance - Introduction To Risk Management (I11) Practice Test

An enzyme functions best at pH 7. When placed at pH 2, its reaction rate falls sharply. What is the best explanation?

The acidic environment can alter the enzyme's shape and active site The substrate is converted into ATP before binding The enzyme gains additional peptide bonds at low pH The enzyme becomes a lipid at low pH

Correct Answer:

The acidic environment can alter the enzyme's shape and active site

Explanation:

Extreme pH can disrupt ionic and hydrogen-bond interactions that help maintain protein shape. A changed active site can reduce substrate binding and catalytic activity.

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