Archer CAT Practice Test

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Which medication is a full agonist used daily for opioid use disorder treatment?
Correct Answer:
Methadone
Explanation:
Methadone is the correct choice, as it is a full agonist that is commonly used in the daily treatment of opioid use disorder. As a long-acting synthetic opioid, methadone works by activating the opioid receptors in the brain, helping to alleviate withdrawal symptoms and cravings in individuals who are dependent on opioids. This characteristic allows it to stabilize patients in a treatment program, making it effective for long-term management of opioid dependency. Unlike partial agonists, which activate the receptors to a lesser degree (such as buprenorphine), methadone fully engages the opioid receptors, providing more consistent and complete relief from withdrawal symptoms. Naltrexone, in contrast, is an opioid antagonist and does not activate opioid receptors, effectively blocking the effects of opioids rather than treating dependence. Bupropion is an antidepressant that is not used for treating opioid use disorder, and while buprenorphine is indeed used in treatment, it is classified as a partial agonist due to its limited activation of the opioid receptors compared to a full agonist like methadone. Thus, methadone's full agonist properties are what make it a standard option for this particular type of treatment.

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