ASCP Technologist In Microbiology (M)

A buffer solution has maximum resistance to pH change (maximum buffer capacity) when which condition is met?

The ratio [A⁻]/[HA] = 10 The concentration of the weak acid greatly exceeds the conjugate base concentration The molar concentrations of weak acid and conjugate base are equal The solution pH equals twice the pKa of the weak acid

Correct Answer:

The molar concentrations of weak acid and conjugate base are equal

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