Inpatient Obstetric Nurse (NCC) Practice Exam

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Which antihypertensive is preferred for acute management in pregnant women?
Correct Answer:
Hydralazine
Explanation:
Hydralazine is the preferred antihypertensive for the acute management of hypertension in pregnant women primarily due to its vasodilatory properties and effectiveness in rapidly lowering blood pressure. It works by directly relaxing the vascular smooth muscle, leading to a decrease in systemic vascular resistance and subsequently lowering blood pressure. This drug has a well-established safety profile during pregnancy, making it a common choice for treating hypertensive emergencies like severe preeclampsia or eclampsia. Its ability to improve placental perfusion while controlling maternal blood pressure is a key factor in its preference over other antihypertensives in the acute setting. In contrast, other options may pose risks; for example, enalapril, an ACE inhibitor, is contraindicated during pregnancy due to its association with fetal renal impairment and other adverse outcomes. Hydrochlorothiazide, a thiazide diuretic, is generally not used for acute management in pregnant women as it can decrease blood volume and potentially compromise placental blood flow. Atenolol, a beta-blocker, is not typically recommended during pregnancy as it has been associated with intrauterine growth restriction and other fetal issues. This is why hydralazine is favored in these critical situations in obstetric

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