Arab Board Oncology Part 1 Practice Questions - Arab Board Medical Oncology Primary (Part 1) Written Examination - الامتحان الأولي لاختصاص طب الأورام (ABHS) Exam

Access More Questions

Under normoxic cellular conditions, how is the alpha subunit of hypoxia-inducible factor 1 (HIF-1alpha) targeted for rapid proteasomal degradation?

Hydroxylation of specific proline residues by prolyl hydroxylase domain (PHD) proteins, facilitating binding to pVHL Phosphorylation by glycogen synthase kinase 3 beta (GSK3beta), causing MDM2-mediated ubiquitination Direct sumoylation by SENP1, preventing nuclear export Cleavage by caspase-3 upon release from the inner mitochondrial membrane

Correct Answer:

Hydroxylation of specific proline residues by prolyl hydroxylase domain (PHD) proteins, facilitating binding to pVHL

Access more questions from this quiz

Continue to Arab Board Oncology Part 1 Practice Questions - Arab Board Medical Oncology Primary (Part 1) Written Examination - الامتحان الأولي لاختصاص طب الأورام (ABHS) Exam for more practice questions and the full quiz experience.

Access More Questions