CMSA Cert Allergology(SA) Phys Practice Questions - CMSA Sub-specialty Certificate In Allergology Cert Allerg(SA) Phys - South Africa Exam

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A 32-year-old male presents with recurrent episodes of unprovoked non-pruritic abdominal pain and facial swelling without urticaria. Laboratory evaluation reveals C4 < 5 mg/dL. Which combination of test results confirms Hereditary Angioedema Type II as opposed to Type I?

Low C1-INH antigenic protein level with proportionally low C1-INH functional activity Elevated factor XII activity with normal C4, normal C1-INH antigen, and normal C1-INH function Low C1q antigenic level with normal C1-INH antigenic level and normal C1-INH function Normal or elevated C1-inhibitor (C1-INH) antigenic protein level with low C1-INH functional activity

Correct Answer:

Normal or elevated C1-inhibitor (C1-INH) antigenic protein level with low C1-INH functional activity

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