CMSA FC Path(SA) Anatomical Pathology - South Africa Practice Questions - Fellowship Of The College Of Pathologists Of South Africa - Anatomical Pathology Exam

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Histological examination of tissue under polarized light following Congo red staining demonstrates apple-green birefringence in amyloid deposits. What physical protein conformation accounts for this optical property?

Parallel alpha-helical coiled-coil structure Anti-parallel cross-beta-pleated sheet conformation Random coil triple-helix polymer Triple-stranded collagenous superhelix

Correct Answer:

Anti-parallel cross-beta-pleated sheet conformation

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